What is NMN?
NMN (nicotinamide mononucleotide) is a naturally occurring molecule found in living cells. It is a direct precursor your body can use to make NAD+ (nicotinamide adenine dinucleotide), a coenzyme that powers cellular energy metabolism and day-to-day maintenance. When NAD+ is in short supply, cells may struggle to keep up with everyday demands. NAD+ naturally declines by about 1% every year, so even with a healthy diet and active lifestyle, NAD+ might not keep up with daily demands.
The Roles of NAD+
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Energy Metabolism
NAD+ participates in the reactions that turn food into ATP inside mitochondria. It also supports the electron transport chain, which fuels nearly every cellular function.
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DNA Access & Repair Signaling
NAD+ is consumed by PARP enzymes involved in the cellular response to everyday DNA stressors. Sustaining NAD+ helps ensure these maintenance pathways have the coenzyme they need.
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Sirtuin Activity
Sirtuins rely on NAD+ to influence cellular housekeeping, metabolic signaling, and chromatin regulation—factors tied to how cells adapt to stress and maintain efficiency.
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Mitochondrial Function
NAD+availability supports pathways that help mitochondria produce energy efficiently and manage oxidative workload.
Why do NAD+ levels change with age?
Why do NAD+ levels change with age?
NAD+ tends to decline with age. Three common contributors:
- Higher demand. Everyday stressors can increase the activity of NAD+-consuming enzymes (such as PARPs and CD38), drawing down available pools.
- Lower recycling efficiency. The body’s salvage pathway, which recycles precursors like NMN and NR, may not keep pace as well over time.
- Oxidative load and inflammatory tone. Ongoing cellular housekeeping can further increase NAD+ use.
These shifts can show up as lower day-to-day energy, slower recovery from routine exertion, and less metabolic flexibility. If you feel like your thoughts have slowed down and you can’t make it through a workout, your NAD+ levels might be behind it.
Why NMN is helpful for healthy aging.
Aging involves cumulative cellular work: oxidative load, DNA maintenance, and changing inflammatory tone, all of which increase demand forNAD+. When supply lags behind demand, cells may struggle to keep pace. Damage can accumulate and cells may struggle between repair and normal daily functions.
Aging involves cumulative cellular work: oxidative load, DNA maintenance, and changing
inflammatory tone, all of which increase demand forNAD+. When supply lags behind demand,
cells may struggle to keep pace. Damage can accumulate and cells may struggle between
repair and normal daily functions.
How to use Pure NMN powder.
New to NMN: start with about half a scoop (~250 mg) once daily for one week
Then: consider 1 full scoop (500 mg) once daily, or continue with half a scoop based on preference and tolerance
Timing: Choose a consistent time each day. Morning is ideal to align with circadian NAD+ rhythms.
What to expect from Pure NMN powder?
People use NMN to support day-to-day energy metabolism and to help maintain NAD+ status with age. Some notice changes sooner, others later. Effects and timing vary.
Best results come from consistent use alongside adequate protein, sleep, movement, and a generally healthy routine.
Lifestyle factors can slow the drain of NAD+, and NMN can amplify the benefits of a strong routine by supporting ATP production, mitochondrial efficiency, and NAD+-dependent maintenance pathways so your cells perform reliably day to day at every age.
Certified quality.
Gold Standard Testing.
The Renuē by Science Story: Fueling the Future of Longevity
Renuē by Science was founded on a revolutionary idea: aging is not a fixed path, but a biological process we can positively influence. Driven by cutting-edge research, the brand emerged from a commitment to translate complex science into pure, effective formulas.
Their mission is rooted in a direct, scientific approach to healthspan. They focus on powerful, well-researced molecules like NMN to target the root causes of aging at a cellular level. By prioritizing rigorous purity, third-party testing, and bioavailability, Renuē by Science empowers individuals to take control of their vitality. They are not just a supplement company; they are a partner in the proactive pursuit of a longer, healthier life.
Quality is A Top Priority
Product quality and testing are a priority. We utilize meticulous and extensive 3rd party testing on our products. Each product goes through raw material testing, purity and stability testing – in addition to testing the final product, which many companies do not do.
After production, we send the finished product to test that the capsules or jar has the amount specified on the bottle. That product assurance test has the batch number of the bottle, so customers can confirm the bottle they purchase truly has the quantity of active ingredients specified on the bottle.